Middle East respiratory syndrome coronavirus (MERS-CoV): A cluster analysis with implications for global management of suspected cases
Identifieur interne : 001675 ( Main/Exploration ); précédent : 001674; suivant : 001676Middle East respiratory syndrome coronavirus (MERS-CoV): A cluster analysis with implications for global management of suspected cases
Auteurs : Ziad A. Memish [Arabie saoudite] ; Jaffar A. Al-Tawfiq [Arabie saoudite, États-Unis] ; Rafat F. Alhakeem [Arabie saoudite] ; Abdullah Assiri [Arabie saoudite] ; Khalid D. Alharby [Arabie saoudite] ; Maher S. Almahallawi [Arabie saoudite] ; Mohammed Alkhallawi [Arabie saoudite]Source :
- Travel Medicine and Infectious Disease [ 1477-8939 ] ; 2015.
Descripteurs français
- KwdFr :
- Analyse de regroupements, Arabie saoudite (épidémiologie), Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Flambées de maladies (), Humains, Infection croisée (transmission), Infection croisée (épidémiologie), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Mâle, Traçage des contacts.
- MESH :
- Wicri :
- geographic : Arabie saoudite.
English descriptors
- KwdEn :
- Cluster Analysis, Contact Tracing, Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Cross Infection (epidemiology), Cross Infection (transmission), Disease Outbreaks (statistics & numerical data), Female, Humans, Male, Middle East Respiratory Syndrome Coronavirus, Saudi Arabia (epidemiology).
- MESH :
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Coronavirus Infections, Cross Infection.
- statistics & numerical data : Disease Outbreaks.
- transmission : Coronavirus Infections, Cross Infection.
- Cluster Analysis, Contact Tracing, Female, Humans, Male, Middle East Respiratory Syndrome Coronavirus.
Abstract
Since the initial description of the Middle East respiratory syndrome (MERS) in September 2012, a total of 1038 cases of MERS-CoV including 460 deaths have been reported from Saudi Arabia. From August 24, 2013 to September 3, 2013, a total of 397 patients and contacts were tested for MERS-CoV. Of those tested, there were 18 (4.5%) MERS-CoV cases reported in Al-Madinah al-Munawwarah with one large cluster. In this report, we describe the outcome, epidemiology and clinical characteristics of this cluster of which 4 cases involved healthcare workers. Fourteen cases appeared to be linked to one cluster involving healthcare workers (HCWs), family and patient contacts. Of the 18 cases, five (including 2 HCWs) were community acquired, two were household contacts, and 11 were healthcare associated (including 4 HCWs). All except 4 cases were symptomatic and the case fatality rate was 39% (7 of 18). The outbreak resulted in human to human transmission of an estimated 6 cases. Contact screening showed positive test in 1 of 56 (1.8%) household contacts, and 3 of 250 (1.2%) HCWs.
Url:
DOI: 10.1016/j.tmaid.2015.06.012
PubMed: 26211569
PubMed Central: 7110629
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p>Since the initial description of the Middle East respiratory syndrome (MERS) in September 2012, a total of 1038 cases of MERS-CoV including 460 deaths have been reported from Saudi Arabia. From August 24, 2013 to September 3, 2013, a total of 397 patients and contacts were tested for MERS-CoV. Of those tested, there were 18 (4.5%) MERS-CoV cases reported in Al-Madinah al-Munawwarah with one large cluster. In this report, we describe the outcome, epidemiology and clinical characteristics of this cluster of which 4 cases involved healthcare workers. Fourteen cases appeared to be linked to one cluster involving healthcare workers (HCWs), family and patient contacts. Of the 18 cases, five (including 2 HCWs) were community acquired, two were household contacts, and 11 were healthcare associated (including 4 HCWs). All except 4 cases were symptomatic and the case fatality rate was 39% (7 of 18). The outbreak resulted in human to human transmission of an estimated 6 cases. Contact screening showed positive test in 1 of 56 (1.8%) household contacts, and 3 of 250 (1.2%) HCWs.</p>
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</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Arabie saoudite</li>
<li>États-Unis</li>
</country>
<region><li>Indiana</li>
</region>
</list>
<tree><country name="Arabie saoudite"><noRegion><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name>
</noRegion>
<name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A." last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name>
<name sortKey="Alhakeem, Rafat F" sort="Alhakeem, Rafat F" uniqKey="Alhakeem R" first="Rafat F." last="Alhakeem">Rafat F. Alhakeem</name>
<name sortKey="Alharby, Khalid D" sort="Alharby, Khalid D" uniqKey="Alharby K" first="Khalid D." last="Alharby">Khalid D. Alharby</name>
<name sortKey="Alkhallawi, Mohammed" sort="Alkhallawi, Mohammed" uniqKey="Alkhallawi M" first="Mohammed" last="Alkhallawi">Mohammed Alkhallawi</name>
<name sortKey="Almahallawi, Maher S" sort="Almahallawi, Maher S" uniqKey="Almahallawi M" first="Maher S." last="Almahallawi">Maher S. Almahallawi</name>
<name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name>
<name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A." last="Memish">Ziad A. Memish</name>
</country>
<country name="États-Unis"><region name="Indiana"><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A." last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name>
</region>
</country>
</tree>
</affiliations>
</record>
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